Potassium homoeostasis and pathophysiology of hyperkalaemia
نویسندگان
چکیده
منابع مشابه
The role of adrenal medullary catecholamines in potassium homoeostasis.
The concentration of potassium in plasma is maintained within the normal range in man by many different physiological factors. The kidney is obviously of prime importance, as demonstrated by the hyperkalaemia which develops in renal failure [ 11. Several circulating hormones are, however, also of importance in potassium homoeostasis. Insulin enhances the uptake of potassium in muscle, liver and...
متن کاملPhysiology and pathophysiology of potassium homeostasis.
Total body potassium content and proper distribution of potassium across the cell membrane is of critical importance for normal cellular function. Potassium homeostasis is maintained by several different methods. In the kidney, total body potassium content is achieved by alterations in renal excretion of potassium in response to variations in intake. Insulin and beta-adrenergic tone play critic...
متن کاملDisorders of potassium homeostasis: pathophysiology and management.
Disorders of potassium homeostasis are common electrolyte abnormalities encountered in hospitalized patients. Hypokalemia and hyperkalemia have been estimated to occur in about 21% and 3% of hospitalized patients, respectively; though the morbidity and mortality associated with the latter is significantly higher. Potassium is a predominantly intracellular ion and the understanding of its dynami...
متن کاملHyperkalaemia.
Hyperkalaemia is defined as serum potassium concentration greater than 5.5 mmol/l. Its prevalence in the general population is unknown, but it is thought to occur in 1-10% of patients admitted to hospital.1 The rate of morbidity and mortality associated with hyperkalaemia has risen greatly with the use of drugs that target the renin-angiotensin system, and since publication 10 years ago of a ra...
متن کاملHypokalaemia and hyperkalaemia.
Disturbances in potassium homoeostasis presenting as low or high serum potassium are common, especially among hospitalised patients. Given the fact that untreated hypokalaemia or hyperkalaemia is associated with high morbidity and mortality, it is critical to recognise and treat these disorders promptly. In this article, normal potassium homoeostasis is reviewed initially and then a pathophysio...
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ژورنال
عنوان ژورنال: European Heart Journal Supplements
سال: 2019
ISSN: 1520-765X,1554-2815
DOI: 10.1093/eurheartj/suy033